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c-FOS antibody (pSer362) (AbBy Fluor® 350)

This Rabbit Polyclonal antibody specifically detects c-FOS in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Rat and Mouse.
Catalog No. ABIN1693477

Quick Overview for c-FOS antibody (pSer362) (AbBy Fluor® 350) (ABIN1693477)

Target

See all c-FOS (c-Fos) Antibodies
c-FOS (c-Fos) (c-Fos)

Reactivity

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Human, Rat, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This c-FOS antibody is conjugated to AbBy Fluor® 350

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    pSer362

    Cross-Reactivity

    Human, Mouse, Rat

    Predicted Reactivity

    Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Ser362

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    c-FOS (c-Fos) (c-Fos)

    Alternative Name

    c-Fos

    Background

    Synonyms: p55, AP-1, C-FOS, Proto-oncogene c-Fos, Cellular oncogene fos, G/G1 switch regulatory protein 7, FOS, GS7

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Gene ID

    2353

    UniProt

    P01100

    Pathways

    S100 Proteins
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