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Cytokeratin 18 antibody (pSer52) (AbBy Fluor® 647)

This anti-Cytokeratin 18 antibody is a Rabbit Polyclonal antibody detecting Cytokeratin 18 in WB, IF (cc) and IF (p). Suitable for Mouse.
Catalog No. ABIN1699812

Quick Overview for Cytokeratin 18 antibody (pSer52) (AbBy Fluor® 647) (ABIN1699812)

Target

See all Cytokeratin 18 (KRT18) Antibodies
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity

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Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Cytokeratin 18 antibody is conjugated to AbBy Fluor® 647

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    pSer52

    Cross-Reactivity

    Mouse

    Predicted Reactivity

    Rat

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from mouse CK18 around the phosphorylation site of Ser52 [SR(p-S)VW]

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Alternative Name

    CK18

    Background

    Synonyms: Keratin, type I cytoskeletal 18, Cytokeratin endo B, Keratin D, Cytokeratin-18, CK-18, Keratin-18, K18, Krt18, Kerd, Krt1-18

    Background: When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

    Gene ID

    16668

    Pathways

    Apoptosis, Caspase Cascade in Apoptosis
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