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BPY2 antibody (AA 51-106) (Biotin)

BPY2 Reactivity: Human WB, IHC (fro), IHC (p), ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1699873
  • Target See all BPY2 Antibodies
    BPY2 (Basic Charge, Y-Linked, 2 (BPY2))
    Binding Specificity
    • 14
    • 1
    AA 51-106
    Reactivity
    Human
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BPY2 antibody is conjugated to Biotin
    Application
    • 15
    • 13
    • 13
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BPY2
    Isotype
    IgG
    Top Product
    Discover our top product BPY2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    BPY2 (Basic Charge, Y-Linked, 2 (BPY2))
    Alternative Name
    BPY2 (BPY2 Products)
    Synonyms
    BPY2A antibody, VCY2 antibody, VCY2A antibody, basic charge, Y-linked, 2 antibody, BPY2 antibody
    Background

    Synonyms: Basic charge, Basic charge Y linked 2, Basic charge Y linked 2C, Basic protein on Y chromosome 2, BPY2A, BPY2B, BPY2C, Testis specic basic protein on Y 2, Testis specic basic protein Y 2, Testis-specic basic protein Y 2, Variable charge Y linked 2, Variably charged protein Y 2, VCY2, VCY2_HUMAN, VCY2A, VCY2B, VCY2C, Y-linked 2.

    Background: Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.

    Gene ID
    442867
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