FUT6 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1699993

This Rabbit Polyclonal antibody specifically detects FUT6 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for FUT6 antibody (AA 101-200) (Biotin) (ABIN1699993)

Target: FUT6 (Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) (FUT6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT6 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FUT6 Antibody (Biotin)

Binding Specificity: AA 101-200

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FUT6/FucT-VI

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FUT6

Target: FUT6 (Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) (FUT6))

Alternative Name: FUT6

Background:

Synonyms: Alpha 1,3 fucosyltransferase, EC=2.4.1.65, FCT3A, Fuc TVI, Fucosyltransferase 6, Fucosyltransferase VI, FucT VI, Galactoside 3 L fucosyltransferase, FUT6_HUMAN.

Background: Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6).

Gene ID: 2528