HDAC4 antibody (pSer246) (Biotin)

Catalog No. ABIN1700128

This Rabbit Polyclonal antibody specifically detects HDAC4 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for HDAC4 antibody (pSer246) (Biotin) (ABIN1700128)

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC4 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HDAC4 Antibody (Biotin)

Binding Specificity: pSer246

Purification: purified by Protein A

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of pSer246

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4 °C for 12 months

Expiry Date: 12 months

Target Details for HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Alternative Name: HDAC4

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Gene ID: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process