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Complement Component C9b (C9b) (AA 251-350) antibody (Biotin)

C9b Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1701212
  • Target See all Complement Component C9b (C9b) Antibodies
    Complement Component C9b (C9b)
    Binding Specificity
    • 15
    • 15
    AA 251-350
    Reactivity
    Human, Mouse
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Biotin
    Application
    • 30
    • 14
    • 13
    • 13
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Complement component C9b
    Isotype
    IgG
    Top Product
    Discover our top product C9b Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Complement Component C9b (C9b)
    Alternative Name
    Complement component C9b (C9b Products)
    Synonyms
    C9 antibody, complement C9 antibody, proteasome (prosome, macropain) subunit, alpha type 4 antibody, C9 antibody, Psma4 antibody
    Background

    Synonyms: CO9_HUMAN, Complement component C9, Complementcomponent C9b.

    Background: C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 Molecules. These polymerized C9 Molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.

    Gene ID
    735
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