GFM2 antibody (AA 151-250) (Biotin)

Catalog No. ABIN1701298

This Rabbit Polyclonal antibody specifically detects GFM2 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Rat.

Quick Overview for GFM2 antibody (AA 151-250) (Biotin) (ABIN1701298)

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GFM2 Antibody (Biotin)

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GFM2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: GFM2

Background:

Synonyms: EF-G2mt, EFG2, EFG2mt, elongation factor G 2, mitochondrial, Elongation factor G2, G elongation factor mitochondrial 2, GFM2, hEFG2, mEFG 2, mEFG2, Mitochondrial elongation factor G2, mitochondrial ribosome recycling factor 2, MRRF2, MST027, MSTP027, OTTHUMP00000222951, OTTHUMP00000222952, ribosome-releasing factor 2, mitochondrial, RRF2, RRF2mt.

Background: GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.

Gene ID: 84340

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization