GFM2 antibody (C-Term)

Catalog No. ABIN926528

Product Details anti-GFM2 Antibody

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: GFM2 antibody was raised in rabbit using the C terminal of GFM2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GFM2 Blocking Peptide, catalog no. 33R-9354, is also available for use as a blocking control in assays to test for specificity of this GFM2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: GFM2 (GFM2 Products)

Synonyms: RGD1309854 antibody, 6530419G12Rik antibody, A930009M04Rik antibody, EF-G2mt antibody, EFG2 antibody, MST027 antibody, RRF2mt antibody, mEF-G 2 antibody, si:dkey-35i22.3 antibody, zgc:153835 antibody, MRRF2 antibody, RRF2 antibody, hEFG2 antibody, ST15 antibody, G elongation factor, mitochondrial 2 antibody, G elongation factor mitochondrial 2 antibody, ribosome-releasing factor 2, mitochondrial antibody, reversion inducing cysteine rich protein with kazal motifs antibody, Gfm2 antibody, GFM2 antibody, gfm2 antibody, LOC662021 antibody, RECK antibody

Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Synonyms: Polyclonal GFM2 antibody, Anti-GFM2 antibody, G elongation factor, mitochondrial 2 antibody, EFG2 antibody, MRRF2 antibody, MST027 antibody, RRF2 antibody, RRF2mt antibody, hEFG2 antibody.

Pathways: Ribonucleoprotein Complex Subunit Organization