GFM2 antibody (C-Term)

Catalog No. ABIN926528

The Rabbit Polyclonal anti-GFM2 antibody is suitable to detect GFM2 in samples from Human. It has been validated for WB.

Quick Overview for GFM2 antibody (C-Term) (ABIN926528)

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GFM2 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: GFM2 antibody was raised in rabbit using the C terminal of GFM2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GFM2 Blocking Peptide, (ABIN5613750), is also available for use as a blocking control in assays to test for specificity of this GFM2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: GFM2

Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Synonyms: Polyclonal GFM2 antibody, Anti-GFM2 antibody, G elongation factor, mitochondrial 2 antibody, EFG2 antibody, MRRF2 antibody, MST027 antibody, RRF2 antibody, RRF2mt antibody, hEFG2 antibody.

Pathways: Ribonucleoprotein Complex Subunit Organization