GFM2 antibody (C-Term)

Catalog No. ABIN2788489

The Rabbit Polyclonal anti-GFM2 antibody (ABIN2788489) specifically detects GFM2 in WB. The antibody is reactive with Human, Horse, Pig, Cow and Dog samples.

Quick Overview for GFM2 antibody (C-Term) (ABIN2788489)

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Reactivity: Human, Horse, Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GFM2 Antibody

Binding Specificity: C-Term

Purpose: GFM2 Antibody - C-terminal region

Sequence: TVGLKHTATG DTIVSSKSSA LAAARRAERE GEKKHRQNNE AERLLLAGVE

Predicted Reactivity: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%

Characteristics: This is a rabbit polyclonal antibody against GFM2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GFM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60546-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: GFM2

Background:

Background Information: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.

Gene Name: G elongation factor, mitochondrial 2

Alternative Symbols: RRF, EFG2, RRF2, MRRF2, hEFG2, MST027, RRF2mt, EF-G2mt, MSTP027, mEF-G 2

Protein Name: Ribosome-releasing factor 2, mitochondrial

Molecular Weight: 86kDa

Gene ID: 84340

NCBI Accession: NP_115756

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization