GFM2 antibody (C-Term)

Catalog No. ABIN2788489

Product Details anti-GFM2 Antibody

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Binding Specificity: C-Term

Reactivity: Human, Horse, Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TVGLKHTATG DTIVSSKSSA LAAARRAERE GEKKHRQNNE AERLLLAGVE

Predicted Reactivity: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%

Characteristics: This is a rabbit polyclonal antibody against GFM2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GFM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 779 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: GFM2 (GFM2 Products)

Synonyms: RGD1309854 antibody, 6530419G12Rik antibody, A930009M04Rik antibody, EF-G2mt antibody, EFG2 antibody, MST027 antibody, RRF2mt antibody, mEF-G 2 antibody, si:dkey-35i22.3 antibody, zgc:153835 antibody, MRRF2 antibody, RRF2 antibody, hEFG2 antibody, ST15 antibody, G elongation factor, mitochondrial 2 antibody, G elongation factor mitochondrial 2 antibody, ribosome-releasing factor 2, mitochondrial antibody, reversion inducing cysteine rich protein with kazal motifs antibody, Gfm2 antibody, GFM2 antibody, gfm2 antibody, LOC662021 antibody, RECK antibody

Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
Alias Symbols: EFG2, MRRF2, MST027, RRF2, RRF2mt, hEFG2, EF-G2mt, mEF-G 2
Protein Interaction Partner: TRIM9, BANP, VPS52, TRIM27, UBC,
Protein Size: 779

Molecular Weight: 86 kDa

Gene ID: 84340

NCBI Accession: NM_032380, NP_115756

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization