Chromosome 15 Open Reading Frame 58 (C15orf58) (AA 301-385) antibody (Biotin)

Catalog No. ABIN1701448

This Rabbit Polyclonal antibody specifically detects Chromosome 15 Open Reading Frame 58 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for Chromosome 15 Open Reading Frame 58 (C15orf58) (AA 301-385) antibody (Biotin) (ABIN1701448)

Target: Chromosome 15 Open Reading Frame 58 (C15orf58)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 301-385

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDPGP1/C15orf58

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Chromosome 15 Open Reading Frame 58 (C15orf58)

Alternative Name: GDPGP1/C15orf58

Background:

Synonyms: C15orf58, Chromosome 15 open reading frame 58, GDP-D-glucose phosphorylase 1, GDP-D-glucose phosphorylase C15orf58, gdpgp1, GDPP1_HUMAN, VTC2.

Background: Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. The LOC390637 gene product has been provisionally designated LOC390637 pending further characterization.

Gene ID: 390637