DCAF7 antibody (AA 2-100) (Cy3)

Catalog No. ABIN1702240

This Rabbit Polyclonal antibody specifically detects DCAF7 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for DCAF7 antibody (AA 2-100) (Cy3) (ABIN1702240)

Target: DCAF7 (DDB1 and CUL4 Associated Factor 7 (DCAF7))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF7 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DCAF7 Antibody (Cy3)

Binding Specificity: AA 2-100

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WDR68

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DCAF7

Target: DCAF7 (DDB1 and CUL4 Associated Factor 7 (DCAF7))

Alternative Name: Wdr68

Background:

Synonyms: AN11, Dcaf7, DCAF7_HUMAN, DDB1- and CUL4-associated factor 7, HAN11, Human anthocyanin, Petunia, Seven WD repeat protein of the AN11 family 1, SWAN 1, WD repeat domain 68, WD repeat protein An11 homolog, WD repeat-containing protein 68, WD repeat-containing protein An11 homolog, WDR68.

Background: Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Pathways: SARS-CoV-2 Protein Interactome