ARFRP1 antibody (AA 1-100) (Cy3)

Catalog No. ABIN1702903

This Rabbit Polyclonal antibody specifically detects ARFRP1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for ARFRP1 antibody (AA 1-100) (Cy3) (ABIN1702903)

Target: ARFRP1 (ADP-Ribosylation Factor Related Protein 1 (ARFRP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARFRP1 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ARFRP1 Antibody (Cy3)

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARFRP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ARFRP1

Target: ARFRP1 (ADP-Ribosylation Factor Related Protein 1 (ARFRP1))

Alternative Name: ARFRP1

Background:

Synonyms: ADP ribosylation factor related protein 1, ARF related protein 1, ARF related protein, ARL 18, ARL18, ARP 1, ARP, ARP1, Helicase like protein NHL, MGC6837, SCG10 like protein, ARFRP_HUMAN.

Background: The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis.

Gene ID: 10139