GPR20 antibody (AA 51-150) (Cy5)
Quick Overview for GPR20 antibody (AA 51-150) (Cy5) (ABIN1703919)
Target
See all GPR20 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 51-150
-
Cross-Reactivity
- Human
-
Purification
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human G protein coupled receptor 20
-
Isotype
- IgG
-
-
-
-
Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Expiry Date
- 12 months
-
-
- GPR20 (G Protein-Coupled Receptor 20 (GPR20))
-
Alternative Name
- GPR20
-
Background
-
Synonyms: G protein coupled receptor 20, G-protein coupled receptor 20, Gpr20, GPR20_HUMAN, GPCR GPR20.
Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR20 is a 358 amino acid membrane protein that constitutively activates G(i) proteins without ligand stimulation. Also, GPR20 may be involved in the control of intracellular cAMP levels and mitogenic signaling. Interestingly, GPR20 is expressed in liver and certain regions of the brain, including putamen, caudate and thalamus, but is not expressed in hypothalamus, pons and frontal cortex.
-
Gene ID
- 2843
Target
-