Cofilin 1 (CFL1) (pSer24) antibody (Cy5) Primary Antibody
CFL1
Reactivity: Human, Mouse, Rat
IF (p)
Host: Rabbit
Polyclonal
Catalog No. ABIN1704204
$442.20
Plus shipping costs $45.00
100 μL
local_shipping
Shipping to:
United States
Delivery in 11 to 16 Business Days
-
- Target
- Binding Specificity
- pSer24
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugate
- Cy5
- Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Ser24
- Isotype
- IgG
-
-
- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C
- Expiry Date
- 12 months
-
- Target
- Alternative Name
- Cofilin (CFL1 Antibody Abstract)
- Background
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Synonyms: Cofilin/CFL1 Ser24, 18 kDa phosphoprotein, CFL 1, CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, COF1_HUMAN.
- Gene ID
- 1072
- Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
You are here: