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Cofilin antibody (pSer24) (Cy5)

CFL1 Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal Cy5

Catalog No. ABIN1704204

Datasheet as PDF

Target See all Cofilin (CFL1) Antibodies

Cofilin (CFL1) (Cofilin 1 (CFL1))
Binding Specificity
18

17

16

14

11

8

7

7

7

5

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer24
Reactivity
131

92

88

5

5

5

4

1

1

1

1
Rat
Host
136

8

2
Rabbit
Compatible Secondaries
Clonality
136

9
Polyclonal
Conjugate
70

10

10

7

6

4

3

3

3

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1
This Cofilin antibody is conjugated to Cy5
Application
70

61

44

42

40

40

29

26

16

12

7

7

3

3

3

2

2
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity

Rat

Predicted Reactivity

Human,Mouse,Dog,Cow,Pig,Chicken,Guinea Pig

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Ser24

Isotype

IgG

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CFL1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

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CFL1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 70-98) antibody
CFL1 Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB23947 unconjugated

anti-Cofilin 1 (CFL1) (AA 1-100) antibody
CFL1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 2-166) antibody
CFL1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 4-144) antibody
CFL1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (pSer3) antibody
CFL1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 4-32), (N-Term) antibody
CFL1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB20525 unconjugated

Application Notes

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name

Cofilin (CFL1 Products)

Background

Synonyms: Cofilin/CFL1 Ser24, 18 kDa phosphoprotein, CFL 1, CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, COF1_HUMAN.
Background: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Gene ID

1072

Pathways

Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events