Nemo-Like Kinase (NLK) (pThr298) antibody (Cy5)

Details for Product No. ABIN1704455
Antigen
Epitope
pThr298
19
14
10
9
8
7
4
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
110
59
46
3
2
2
1
1
1
1
1
1
Host
Rabbit
104
12
Clonality
Polyclonal
Conjugate
Cy5
8
7
7
5
5
5
3
3
3
3
3
3
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
86
47
43
25
13
12
9
9
2
1
1
1
Options
Immunogen KLH conjugated synthetic phosphopeptide derived from human Nemo-like kinase around the phosphorylation site of Thr298
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Nemo-Like Kinase (NLK Antibody Abstract)
Background

Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. (referenced from swissprot)

Synonyms: Nemo-like kinase Thr298, Nemo-like kinase T298, p-Nemo-like kinase Thr298, p-Nemo-like kinase T298, DKFZp761G1211, FLJ21033, LAK1, Nemo like kinase, Nemo-like kinase, Nlk, NLK_HUMAN, Protein LAK1, Serine/threonine protein kinase NLK, Serine/threonine-protein kinase NLK.

Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months