ICK antibody (Tyr159) (Cy5)

Catalog No. ABIN1704520

Product Details anti-ICK Antibody (Cy5)

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Binding Specificity: Tyr159

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICK antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ICK(Tyr159)

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Alternative Name: Ick (ICK Products)

Synonyms: ICK antibody, ECO antibody, LCK2 antibody, MRK antibody, 2210420N10Rik antibody, AI848300 antibody, Mrk antibody, intestinal cell kinase antibody, intestinal cell (MAK-like) kinase antibody, ICK antibody, ick antibody, Ick antibody

Background:

Synonyms: ICKTyr159, 2210420N10Rik, AI848300, ECO, ICK_HUMAN, Heart serine threonine protein kinase, hICK, Intestinal cell MAK like kinase, Intestinal cell kinase, KIAA0936, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MAK related kinase, MGC46090, mICK, MRK, OTTMUSP00000041856, OTTMUSP00000041857, Serine/threonine-protein kinase ICK, Serine/threonine protein kinase ICK.

Background: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.