BAMBI antibody (AA 101-200) (Cy5)

Catalog No. ABIN1704611

The Rabbit Polyclonal anti-BAMBI antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect BAMBI in samples from Human, Rat, Mouse and Pig.

Quick Overview for BAMBI antibody (AA 101-200) (Cy5) (ABIN1704611)

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Reactivity: Human, Rat, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAMBI antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-BAMBI Antibody (Cy5)

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Pig, Rat

Predicted Reactivity: Dog,Cow,Sheep,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BAMBI

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BAMBI

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Alternative Name: BAMBI

Background:

Synonyms: NMA, BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMA, BAMBI

Background: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

Gene ID: 25805

UniProt: Q13145