BAMBI antibody

Catalog No. ABIN7227460

This Rabbit Polyclonal antibody specifically detects BAMBI in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for BAMBI antibody (ABIN7227460)

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAMBI antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BAMBI Antibody

Purpose: Rabbit Anti-BAMBI Polyclonal Antibody

Specificity: The antibody detects endogenous levels of BAMBI protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human BAMBI protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BAMBI

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Alternative Name: BAMBI

Background: BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMABAMBI gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.

Molecular Weight: 28kD

Gene ID: 25805

UniProt: Q13145