S100A6 antibody (AA 15-70) (Cy5)

Catalog No. ABIN1704757

This Rabbit Polyclonal antibody specifically detects S100A6 in IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for S100A6 antibody (AA 15-70) (Cy5) (ABIN1704757)

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A6 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-S100A6 Antibody (Cy5)

Binding Specificity: AA 15-70

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human S100A6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for S100A6

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S100A6

Background:

Synonyms: S100 alpha 6 PRA, Calcyclin, PRAGrowth factor inducible protein 2A9, Prolactin receptor associated protein, Prolactin receptor-associated protein, Protein S100 A6, Protein S100-A6, S100 A6, S100 calcium binding protein A6 calcyclin, S100 calcium binding protein A6, S100 calcium-binding protein A6, S100A6, S100A6_HUMAN, S100-A6, 2A9, 5B10, CABP, CACY, Calcyclin, Growth factor inducible protein 2A9, Growth factor-inducible protein 2A9, MLN 4, MLN4.

Background: Calcyclin, also known as Protein S100-A6, growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.

Gene ID: 10014

Pathways: S100 Proteins