TAX1BP1 antibody (AA 241-340) (Cy5.5)

Catalog No. ABIN1705852

Product Details anti-TAX1BP1 Antibody (Cy5.5)

Target: TAX1BP1 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (TAX1BP1))

Binding Specificity: AA 241-340

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAX1BP1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRAF6BP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TAX1BP1

Target: TAX1BP1 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (TAX1BP1))

Alternative Name: TAX1BP1 (TAX1BP1 Products)

Background:

Synonyms: Human T cell leukemia virus type 1-binding protein, Liver regeneration-related protein LRRG004, MGC94031, PRO0105, T6BP, Tax1 human T cell leukemia virus type I binding protein 1, Tax1 human T cell leukemia virus type I binding protein, Tax1 binding protein 1, Tax1 binding protein, Tax1-binding protein 1, Tax1-binding protein 1 homolog, TAX1BP1, TAX1BP1 protein, tax1bp1b, TAXB1_HUMAN, TRAF 6 binding protein, TRAF6 binding protein, TRAF6 binding protein T6BP, TRAF6-binding protein, TRAF6-interacting protein, TXBP 151, TXBP151

Background: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.

Gene ID: 8887

UniProt: Q86VP1

Pathways: TLR Signaling