ARPC4 antibody (AA 1-100) (Cy5.5)

Catalog No. ABIN1705919

The Rabbit Polyclonal anti-ARPC4 antibody is suitable to detect ARPC4 in samples from Xenopus laevis. It has been validated for IF (cc) and IF (p).

Quick Overview for ARPC4 antibody (AA 1-100) (Cy5.5) (ABIN1705919)

Target: ARPC4 (Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))

Reactivity: Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPC4 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ARPC4 Antibody (Cy5.5)

Binding Specificity: AA 1-100

Cross-Reactivity: Xenopus laevis

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARPC4/p20-ARC

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ARPC4

Target: ARPC4 (Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))

Alternative Name: ARPC4/p20-ARC

Background:

Synonyms: Actin related protein 2/3 complex subunit 4, Actin related protein 2/3 complex subunit 4 20 kD, Actin related protein 2/3 complex subunit 4 20 kDa, Actin-related protein 2/3 complex subunit 4, ARC20, Arp2/3 complex 20 kDa subunit, Arp2/3 protein complex subunit p20, ARPC 4, ARPC4, ARPC4_HUMAN, MGC13544, OTTHUMP00000165252, OTTHUMP00000207520, p20 Arc, p20-ARC, p20ARC.

Background: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].

Gene ID: 10093

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization