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Orexin A antibody (Cy7)

The Rabbit Polyclonal anti-Orexin A antibody has been validated for WB and IF (p). It is suitable to detect Orexin A in samples from Human.
Catalog No. ABIN1707455

Quick Overview for Orexin A antibody (Cy7) (ABIN1707455)

Target

See all Orexin A (OXA) Antibodies
Orexin A (OXA)

Reactivity

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Human

Host

  • 28
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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 2
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This Orexin A antibody is conjugated to Cy7

Application

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Cross-Reactivity

    Human

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Orexin A

    Isotype

    IgG
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Orexin A (OXA)

    Alternative Name

    Orexin A

    Background

    Synonyms: HCRT 1, HCRT, HCRT1, HCRT2, Hypocretin orexin neuropeptide precursor, Hypocretin 1, Hypocretin 2, Hypocretin A, Hypocretin, Hypocretin neuropeptide precursor, Hypocretin1, NRCLP1, Orexin A, Orexin, Orexin B, Orexin precursor, OrexinA, OX, PPORX, PPOX, PREPROOREXIN, OREX_HUMAN.

    Background: Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

    Gene ID

    3060

    Pathways

    Synaptic Membrane, Feeding Behaviour
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