DYNC1I1 antibody (AA 1-100) (FITC)

Catalog No. ABIN1709473

This Rabbit Polyclonal antibody specifically detects DYNC1I1 in WB, FACS, IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.

Quick Overview for DYNC1I1 antibody (AA 1-100) (FITC) (ABIN1709473)

Target: DYNC1I1 (Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1I1 antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DYNC1I1 Antibody (FITC)

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DYNC1I1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DYNC1I1

Target: DYNC1I1 (Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1))

Alternative Name: DYNC1I1

Background:

Synonyms: dynein, cytoplasmic, intermediate polypeptide 1, cytoplasmic dynein 1 intermediate chain 1, DH IC-1, dynein intermediate chain 1, cytosolic, cytoplasmic dynein intermediate chain 1, DC1I1_HUMAN, DYNC1I1, DNCI1, DNCIC1, Dynein cytoplasmic intermediate polypeptide 1.

Background: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

Gene ID: 1780

UniProt: O14576