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LIMD1 antibody (AA 21-120) (FITC)

This Rabbit Polyclonal antibody specifically detects LIMD1 in IF (cc) and IF (p). It exhibits reactivity toward Mouse.
Catalog No. ABIN1710019

Quick Overview for LIMD1 antibody (AA 21-120) (FITC) (ABIN1710019)

Target

See all LIMD1 Antibodies
LIMD1 (LIM Domains Containing 1 (LIMD1))

Reactivity

  • 28
  • 21
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Mouse

Host

  • 35
  • 2
Rabbit

Clonality

  • 35
  • 2
Polyclonal

Conjugate

  • 19
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LIMD1 antibody is conjugated to FITC

Application

  • 20
  • 14
  • 12
  • 12
  • 12
  • 8
  • 4
  • 3
  • 2
  • 2
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    Cross-Reactivity

    Mouse

    Predicted Reactivity

    Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Limd1

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    LIMD1 (LIM Domains Containing 1 (LIMD1))

    Alternative Name

    Limd1

    Background

    Synonyms: AW822033, D9Ertd192e, LIM domain-containing protein 1, LIM domains containing 1, LIMD1, LIMD1_HUMAN, OTTHUMP00000164657, OTTHUMP00000210317, rCG_25194.

    Background: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.

    Gene ID

    8994

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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