ACAA1 antibody (AA 231-330) (FITC)

Catalog No. ABIN1710289

This Rabbit Polyclonal antibody specifically detects ACAA1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for ACAA1 antibody (AA 231-330) (FITC) (ABIN1710289)

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ACAA1 Antibody (FITC)

Binding Specificity: AA 231-330

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABLIM3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ACAA1

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Alternative Name: ACAA1

Background:

Synonyms: 3 ketoacyl CoA thiolase peroxisomal, 3-ketoacyl-CoA thiolase, ACAA, ACAA1, Acetyl CoA acyltransferase 1, Acetyl Coenzyme A acyltransferase 1, Acetyl-CoA acyltransferase, Acetyl-Coenzyme A acyltransferase 1 peroxisomal 3 oxoacyl Coenzyme A, Beta ketothiolase, Beta-ketothiolase, Peroxisomal 3 oxoacyl CoA thiolase, Peroxisomal 3 oxoacyl Coenzyme A thiolase, Peroxisomal 3-oxoacyl-CoA thiolase, peroxisomal, PTHIO, THIK_HUMAN, THIO.

Background: ACAA1 is a 424 amino acid member of the thiolase family of enzymes and is involved in lipid metabolism. Localized to the peroxisome, ACAA1 catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. ACAA1 shows high enzymatic activity in liver, kidney, intestine and white adipose tissue in rats, where it exists as two types, namely type A and type B. Human ACAA1 shares 86 % amino acid identity with its rat counterpart, suggesting a conserved function for ACAA1 among different species.

Gene ID: 30

Pathways: Monocarboxylic Acid Catabolic Process