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HPV16 E7 antibody (HRP)

HPV-16 E7 Reactivity: Human Papillomavirus 16 (HPV-16), Virus WB, IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1710867
  • Target See all HPV16 E7 (HPV-16 E7) Antibodies
    HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
    Reactivity
    • 30
    • 18
    • 5
    • 5
    Human Papillomavirus 16 (HPV-16), Virus
    Host
    • 31
    • 12
    Rabbit
    Clonality
    • 31
    • 12
    Polyclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HPV16 E7 antibody is conjugated to HRP
    Application
    • 42
    • 26
    • 17
    • 13
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Virus
    Cross-Reactivity (Details)
    HPV16
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from HPV16 E7 protein
    Isotype
    IgG
    Top Product
    Discover our top product HPV-16 E7 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
    Alternative Name
    HPV16 E7 (HPV-16 E7 Products)
    Synonyms
    transforming protein E7 antibody, E7 antibody
    Target Type
    Viral Protein
    Background

    Synonyms: E7, Human Papilloma Virus, Human papillomavirus type 16 E7, Human papillomavirus type 16 E7, Protein E7, Human Papillomavirus 16 E7, HPV16 E7, E7 protein HPV16, VE7_HPV16.

    Background: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90 % of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

    Gene ID
    1489079
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