Dermcidin antibody (AA 63-109) (HRP)

Catalog No. ABIN1710999

Product Details anti-Dermcidin Antibody (HRP)

Target: Dermcidin (DCD)

Binding Specificity: AA 63-109

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dermcidin antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Dermcidin/DCD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Dermcidin

Target: Dermcidin (DCD)

Alternative Name: Dermcidin/DCD (DCD Products)

Synonyms: AIDD antibody, DCD-1 antibody, DSEP antibody, HCAP antibody, PIF antibody, dermcidin antibody, DCD antibody

Background:

Synonyms: AIDD, DCD 1, dcd, DCD-1, DCD_HUMAN, DSEP, HCAP, P, Preproteolysin.

Background: Antimicrobial peptides participate in the innate response, which may provide a barrier for protection against infection. The Dermcidin gene encodes an antimicrobial peptide DCD-1, which is constitutively expressed in sweat glands, secreted into the sweat, and transported to the epidermal surface. DCD-1 displays antimicrobial activity in response to a variety of pathogenic microorganisms. Overexpression of Dermcidin in breast cancers promotes cell growth and survival, and is coupled with a focal copy number gain of its locus on human chromosome 12q13.2.

Gene ID: 117159