RNASE3 antibody (AA 45-160) (HRP)

Catalog No. ABIN1711003

This Rabbit Polyclonal antibody specifically detects RNASE3 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RNASE3 antibody (AA 45-160) (HRP) (ABIN1711003)

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASE3 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RNASE3 Antibody (HRP)

Binding Specificity: AA 45-160

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECP

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNASE3

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Alternative Name: ECP

Background:

Synonyms: ECP, RNS3, Eosinophil cationic protein, Ribonuclease 3, RNase 3, RNASE3

Background: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Gene ID: 6037

UniProt: P12724