NUP210 antibody (AA 1161-1260) (HRP)

Catalog No. ABIN1711338

This anti-NUP210 antibody is a Rabbit Polyclonal antibody detecting NUP210 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for NUP210 antibody (AA 1161-1260) (HRP) (ABIN1711338)

Target: NUP210 (Nucleoporin 210kDa (NUP210))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP210 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NUP210 Antibody (HRP)

Binding Specificity: AA 1161-1260

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GP210

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NUP210

Target: NUP210 (Nucleoporin 210kDa (NUP210))

Alternative Name: GP210

Background:

Synonyms: FLJ22389, GP 210, KIAA0906, Nuclear envelope pore membrane protein POM 210, Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nucleoporin 210, Nucleoporin 210 kDa, Nucleoporin Nup210, Nucleoporin210, NUP 210, NUP210, PO210_HUMAN, POM 210, POM210, Pore membrane protein of 210 kDa.

Background: The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). gp210, also known as Nup210 (nucleoporin 210 kDa) or POM210, is a 1,887 amino acid single-pass type I membrane protein that localizes to both the endoplasmic reticulum and to the nucleus, specifically within the NPC. Expressed ubiquitously with highest expression in pancreas, testis, lung, ovary and liver, gp210 functions as a nucleoporin that is capable of dimerization and is essential for the assembly, fusion and structural integrity of the NPC. gp210 exists as multiple alternatively spliced isoforms and is subject to post-translational phosphorylation.

Gene ID: 23225

UniProt: Q8TEM1

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection