TESK2 antibody (AA 301-400) (HRP)

Catalog No. ABIN1711492

This Rabbit Polyclonal antibody specifically detects TESK2 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for TESK2 antibody (AA 301-400) (HRP) (ABIN1711492)

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TESK2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TESK2 Antibody (HRP)

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TESK2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TESK2

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Alternative Name: TESK2

Background:

Synonyms: Dual specicity testis specic protein kinase 2, Dual specicity testis-specic protein kinase 2, MGC29168, OTTHUMP00000009093, RP23-109A3.2, Tesk2, TESK2_HUMAN, Testicular protein kinase 2, Testis specic kinase 2.

Background: TESK2 is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning as a dual-specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/threonine residues, thereby mediating intracellular signal transduction pathways. TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis. TESK2 contains one protein kinase domain that is 65 % identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events. Three isoforms of TESK2 are expressed due to alternative splicing.

Gene ID: 10420

Pathways: Cell-Cell Junction Organization