ZBTB5 antibody (AA 581-677) (HRP)

Catalog No. ABIN1711591

This Rabbit Polyclonal antibody specifically detects ZBTB5 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for ZBTB5 antibody (AA 581-677) (HRP) (ABIN1711591)

Target: ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB5 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ZBTB5 Antibody (HRP)

Binding Specificity: AA 581-677

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB5

Target: ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))

Alternative Name: ZBTB5

Background:

Synonyms: 5930421I10, 9430083K24Rik, AI646847, Expressed in brain and neural tube, KIAA0354, mKIAA0354, OTTMUSP00000007812, OTTMUSP00000007813, OTTMUSP00000007814, RP11-397D12.5, RP23-218A4.2, Transcription factor ZNF POZ, Zbtb5, ZBTB5_HUMAN, Zinc finger and BTB domain containing protein 5, Zinc finger and BTB domain-containing protein 5.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.

Gene ID: 9925