ZBTB44 antibody (AA 401-500) (HRP)

Catalog No. ABIN1711756

This Rabbit Polyclonal antibody specifically detects ZBTB44 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ZBTB44 antibody (AA 401-500) (HRP) (ABIN1711756)

Target: ZBTB44 (Zinc Finger and BTB Domain Containing 44 (ZBTB44))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB44 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ZBTB44 Antibody (HRP)

Binding Specificity: AA 401-500

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB44

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB44

Target: ZBTB44 (Zinc Finger and BTB Domain Containing 44 (ZBTB44))

Alternative Name: ZNF851/BTBD15/ZBTB44

Background:

Synonyms: BTB POZ domain containing 15, BTB/POZ domain-containing protein 15, BTBD15, HSPC063, MGC26123, MGC57431, MGC60348, MGC88058, OTTHUMP00000230934, OTTHUMP00000230935, OTTHUMP00000230937, OTTHUMP00000230938, ZBT44_HUMAN, Zbtb44, Zinc finger and BTB domain containing 44, Zinc finger and BTB domain-containing protein 44, Zinc finger protein 851, ZNF851.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying protein. ZBTB44 is a 570 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.

Gene ID: 29068