GBGT1 antibody (AA 251-347) (HRP)

Catalog No. ABIN1711827

This anti-GBGT1 antibody is a Rabbit Polyclonal antibody detecting GBGT1 in WB, ELISA, IHC (fro) and IHC (p). Suitable for Human.

Quick Overview for GBGT1 antibody (AA 251-347) (HRP) (ABIN1711827)

Target: GBGT1 (Globoside alpha-1,3-N-Acetylgalactosaminyltransferase 1 (GBGT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBGT1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GBGT1 Antibody (HRP)

Binding Specificity: AA 251-347

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBGT1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GBGT1

Target: GBGT1 (Globoside alpha-1,3-N-Acetylgalactosaminyltransferase 1 (GBGT1))

Alternative Name: GBGT1

Background:

Synonyms: 3-N-acetylgalactosaminyltransferase 1, A3GALNT, EC=2.4.1.-, Forssman glycolipid synthase-like protein, Forssman glycolipid synthetase FS, Forssman synthetase, FS, GBGT1, GBGT1_HUMAN, Globoside alpha-1, globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, glycolipid synthase-like protein, RP11-326L24.6, UNQ2513, UNQ2513/PRO6002.

Background: GBGT1 is a 347 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 6 family. Localizing to the golgi apparatus membrane, GBGT1 is widely expressed, with high levels found in placenta, ovary and peripheral blood leukocyte, and lower levels expressed in liver, thymus and testis. GBGT1 utilizes manganese as a cofactor, and assists in the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to various substrates, resulting in the formation of glycolipids. Glycolipids are present in most eukaryotic cells and may assist in the adherence of certain pathogens. Existing as two alternatively spliced isoforms, the gene encoding GBGT1 maps to human chromosome 9q34.2 and mouse chromosome 2 A3.

Gene ID: 26301