FLNC antibody (AA 251-350) (HRP)

Catalog No. ABIN1712273

The Rabbit Polyclonal anti-FLNC antibody has been validated for WB, ELISA, IHC (fro), IHC (p). It is suitable to detect FLNC in samples from Mouse, Rat, Chimpanzee.

Quick Overview for FLNC antibody (AA 251-350) (HRP) (ABIN1712273)

Target: FLNC (Filamin C, gamma (FLNC))

Reactivity: Mouse, Rat, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLNC antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FLNC Antibody (HRP)

Binding Specificity: AA 251-350

Cross-Reactivity: Chimpanzee, Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Filamin 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FLNC

Target: FLNC (Filamin C, gamma (FLNC))

Alternative Name: Filamin 2

Background:

Synonyms: ABPA, ABPL, FLN2, MFM5, MPD4, ABP-280, ABP280A, Filamin-C, FLN-C, FLNc, ABP-280-like protein, ABP-L, Actin-binding-like protein, Filamin-2, Gamma-filamin

Background: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.

Gene ID: 2318

UniProt: Q14315