GCP6 antibody (AA 651-750) (HRP)

Catalog No. ABIN1712311

This Rabbit Polyclonal antibody specifically detects GCP6 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for GCP6 antibody (AA 651-750) (HRP) (ABIN1712311)

Target: GCP6 (TUBGCP6) (Tubulin, gamma Complex Associated Protein 6 (TUBGCP6))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCP6 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GCP6 Antibody (HRP)

Binding Specificity: AA 651-750

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCP6

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GCP6

Target: GCP6 (TUBGCP6) (Tubulin, gamma Complex Associated Protein 6 (TUBGCP6))

Alternative Name: GCP6

Background:

Synonyms: GCP 6, TUBGCP6, tubulin, gamma complex associated protein 6, GCP6_HUMAN.

Background: The g-Tubulin complex is composed of g Tubulin and the g-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. g-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the g-Tubulin complex. GCP6 (g-Tubulin complex component 6), also known as TUBGCP6, localizes to the centrosome and is a ubiquitously expressed 1,819 amino acid member of the g-Tubulin complex. Unlike GCP3 and GCP2, GCP6 is not well conserved among eukaryotes. Three isoforms of GCP6 exist due to alternative splicing events.

Gene ID: 85378

Pathways: M Phase