GPI antibody (AA 401-500) (HRP)

Catalog No. ABIN1712326

This Rabbit Polyclonal antibody specifically detects GPI in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for GPI antibody (AA 401-500) (HRP) (ABIN1712326)

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPI antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPI Antibody (HRP)

Binding Specificity: AA 401-500

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glucose 6 phosphate isomerase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GPI

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Alternative Name: GPI

Background:

Synonyms: Glucose 6 phosphate isomerase, AMF, Aurocrine motility factor, Autocrine motility factor, DKFZp686C13233, EC 5.3.1.9, G6PI_HUMAN, Glucose phosphate isomerase, Glucose-6-phosphate isomerase, GNPI, GPI, Gpi1, Hexose monophosphate isomerase, Hexosephosphate isomerase, Neuroleukin, NLK, Oxoisomerase, PHI, Phosphoglucose isomerase, Phosphohexomutase, Phosphohexose isomerase, Phosphosaccharomutase, SA 36, SA-36, SA36, Sperm antigen 36.

Background: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq, Jul 2008].

Gene ID: 51701