IFNAR1 antibody (Tyr466) (PE)

Catalog No. ABIN1712792

The Rabbit Polyclonal anti-IFNAR1 antibody has been validated for FACS. It is suitable to detect IFNAR1 in samples from Human.

Quick Overview for IFNAR1 antibody (Tyr466) (PE) (ABIN1712792)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-IFNAR1 Antibody (PE)

Binding Specificity: Tyr466

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNAR1 around the phosphorylation site of Tyr466

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C for 12 months.

Expiry Date: 12 months

Target Details for IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Alternative Name: Ifnar1

Background: IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Synonyms: Alpha type antiviral protein, AVP, Beta type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, N alpha REC, N alpha REC, N alpha receptor, N alpha/beta Receptor alpha, N beta receptor, Interferon alpha/beta receptor 1, N-alpha/beta receptor 1, N-R-1, NAR, NAR1, NBR, RC, INAR1_HUMAN, Interferon alpha beta and omega receptor 1, Interferon alpha/beta receptor 1, Interferon alpha/beta receptor alpha chain, Interferon beta receptor 1, Type I interferon receptor 1.

Pathways: JAK-STAT Signaling, Hepatitis C