Abeta 1-42 antibody

Catalog No. ABIN1713336

This anti-Abeta 1-42 antibody is a Mouse Monoclonal antibody detecting Abeta 1-42 in WB, IF (p) and IHC (p). Suitable for Human and Rat.

Quick Overview for Abeta 1-42 antibody (ABIN1713336)

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Abeta 1-42 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F4

Product Details anti-Abeta 1-42 Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42)

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Abeta 1-42

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Alternative Name: beta Amyloid 1-42

Background:

Synonyms: NULL

Background: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

Gene ID: 351