Cholera Toxin beta antibody

Catalog No. ABIN1713348

This anti-Cholera Toxin beta antibody is a Rabbit Polyclonal antibody detecting Cholera Toxin beta in WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. Suitable for Vibrio cholerae. This Primary Antibody has been cited in 1 publication.

Quick Overview for Cholera Toxin beta antibody (ABIN1713348)

Target: Cholera Toxin beta

Reactivity: Vibrio cholerae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cholera Toxin beta antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-Cholera Toxin beta Antibody

Cross-Reactivity: Rat

Cross-Reactivity (Details): Cholera Toxin Subunit B

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from CTXB/beta subunit Cholera Toxin

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Cholera Toxin beta antibody (ABIN1713348)

Tanaka, Kuwahara-Otani, Maeda, Minato, Yagi: "Possible Role of the Myelinated Neural Network in the Parietal Peritoneum in Rats as a Mechanoreceptor." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 300, Issue 9, pp. 1662-1669, (2017) (PubMed).

Target Details for Cholera Toxin beta

Target: Cholera Toxin beta

Background:

Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, TOXB, VC1456, CHTB_VIBCH.

Background: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Gene ID: 2613962