SCGB2B27 antibody (AA 401-500)

Catalog No. ABIN1713404

Product Details anti-SCGB2B27 Antibody

Target: SCGB2B27 (Secretoglobin, Family 2B, Member 27 (SCGB2B27))

Binding Specificity: AA 401-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCGB2B27 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2a

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SCGB2B27 antibody (ABIN1713404)

Caine, Lin, Kessler, Sato, Leong, Coburn: "Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival." in: Cellular microbiology, Vol. 19, Issue 12, (2018) (PubMed).

Target Details for SCGB2B27

Target: SCGB2B27 (Secretoglobin, Family 2B, Member 27 (SCGB2B27))

Alternative Name: C2a (SCGB2B27 Products)

Synonyms: Abpbg27 antibody, Scgb2b5 antibody, secretoglobin, family 2B, member 27 antibody, Scgb2b27 antibody

Background:

Synonyms: CO2, ARMD14, Complement C2, C3/C5 convertase, C2

Background: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.

Gene ID: 717

UniProt: P06681