C8orf77 antibody (AA 101-200)

Catalog No. ABIN1713444

The Rabbit Polyclonal anti-C8orf77 antibody (ABIN1713444) specifically detects C8orf77 in ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. The antibody is reactive with Human samples.

Quick Overview for C8orf77 antibody (AA 101-200) (ABIN1713444)

Target: C8orf77 (Chromosome 8 Open Reading Frame 77 (C8orf77))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8orf77 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-C8orf77 Antibody

Binding Specificity: AA 101-200

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C8orf77

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C8orf77

Target: C8orf77 (Chromosome 8 Open Reading Frame 77 (C8orf77))

Alternative Name: C8orf77

Background:

Synonyms: Chromosome 8 open reading frame 77, MGC141859, Putative uncharacterized protein C8orf77,ZNFS1_HUMAN.

Background: C8orf77 (chromosome 8 open reading frame 77) is a 211 amino acid protein encoded by a gene that maps to human chromosome 8q24.3. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.