C9ORF57 antibody (AA 61-160)

Catalog No. ABIN1713451

This Rabbit Polyclonal antibody specifically detects C9ORF57 in ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for C9ORF57 antibody (AA 61-160) (ABIN1713451)

Target: C9ORF57 (Chromosome 9 Open Reading Frame 57 (C9ORF57))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9ORF57 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-C9ORF57 Antibody

Binding Specificity: AA 61-160

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf57

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C9ORF57

Target: C9ORF57 (Chromosome 9 Open Reading Frame 57 (C9ORF57))

Alternative Name: C9orf57

Background:

Synonyms: C9orf57, Chromosome 9 open reading frame 57, CI057_HUMAN, RP11-346E17.3, Uncharacterized protein C9orf57.

Background: Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf57 gene product has been provisionally designated C9orf57 pending further characterization.

Gene ID: 138240