FUZ antibody (AA 101-200)

Catalog No. ABIN1713496

This Rabbit Polyclonal antibody specifically detects FUZ in ELISA, WB, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for FUZ antibody (AA 101-200) (ABIN1713496)

Target: FUZ (Fuzzy Homolog (FUZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUZ antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FUZ Antibody

Binding Specificity: AA 101-200

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FUZ/FUZZY

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FUZ

Target: FUZ (Fuzzy Homolog (FUZ))

Alternative Name: FUZ/FUZZY

Background:

Synonyms: FLJ22688, fuz, FUZZY_HUMAN, Fy, Protein fuzzy homolog.

Background: FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.

Gene ID: 80199

Pathways: Tube Formation, Embryonic Body Morphogenesis