SPANXB1 antibody (AA 1-80)

Catalog No. ABIN1713575

Product Details anti-SPANXB1 Antibody

Target: SPANXB1 (SPANX Family, Member B1 (SPANXB1))

Binding Specificity: AA 1-80

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPANXB1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPANXB1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SPANXB1

Target: SPANXB1 (SPANX Family, Member B1 (SPANXB1))

Alternative Name: SPANXB1 (SPANXB1 Products)

Synonyms: B1 antibody, CT11.2 antibody, SPANX-B antibody, SPANXB antibody, SPANX family member B1 antibody, SPANXB1 antibody

Background:

Synonyms: Cancer/testis antigen 11.2, Cancer/testis antigen family 11, member 2, CT11.2, hCG2036708, Nuclear associated protein SPAN Xb, Nuclear-associated protein SPAN-Xb, Nuclear-associated protein SPAN-Xf, SPAN Xb protein, SPAN Xf, SPANX, SPANX B, SPANX C, SPANX F, SPANX family member B/F, SPANX family, member B1, SPANX family, member B2, SPANX family, member F1, SPANX-B, SPANX-F, SPANXB, SPANXB2, SPANXF, SPANXF1, Sperm protein associated with the nucleus on the X chromosome B/F, Sperm protein associated with the nucleus, X chromosome, family, Sperm protein associated with the nucleus, X chromosome, family member B1, Sperm protein associated with the nucleus, X chromosome, family member B2, SPNXB_HUMAN.

Background: A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.