GMFG antibody (AA 51-142)

Catalog No. ABIN1713818

The Rabbit Polyclonal anti-GMFG antibody is suitable to detect GMFG in samples from Human. It has been validated for WB, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for GMFG antibody (AA 51-142) (ABIN1713818)

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMFG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GMFG Antibody

Binding Specificity: AA 51-142

Purpose: GMFG Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMFG/GMF-gamma

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GMFG

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Alternative Name: GMFG/GMF-gamma

Background:

Synonyms: Glia maturation factor gamma, Glia maturation factor, gamma, GMF GAMMA, GMF-gamma, Gmfg, GMFG_HUMAN, MGC126867.

Background: GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.

Gene ID: 9535