C1orf43 antibody (AA 11-100)

Catalog No. ABIN1714122

Product Details anti-C1orf43 Antibody

Target: C1orf43 (Chromosome 1 Open Reading Frame 43 (C1orf43))

Binding Specificity: AA 11-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf43 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf43

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C1orf43

Target: C1orf43 (Chromosome 1 Open Reading Frame 43 (C1orf43))

Alternative Name: C1orf43 (C1orf43 Products)

Synonyms: NICE-3 antibody, NS5ATP4 antibody, S863-3 antibody, c1orf43 antibody, chromosome 1 open reading frame 43 antibody, chromosome 1 open reading frame 43 L homeolog antibody, C1orf43 antibody, c1orf43.L antibody

Background:

Synonyms: 4933434E20Rik, AI462154, C1orf43, CA043_HUMAN, Chromosome 1 open reading frame 43, HCV NS5A transactivated protein 4, HCV NS5A-transactivated protein 4, Hepatitis C virus NS5A transactivated protein 4, Hepatitis C virus NS5A-transactivated protein 4, HSPC012, Hypothetical protein LOC25912, MGC111001, NICE 3, NICE3, NS5ATP4, OTTHUMP00000034199, OTTHUMP00000034201, OTTHUMP00000034202, Protein NICE 3, Protein NICE-3, Riken cDNA 4933434E20, S863 3, S863-3, Uncharacterized protein C1orf43.

Background: C1orf43, also known as Hepatitis C virus NS5A-transactivated protein 4 and Protein NICE-3, is a 253 amino acid single-pass membrane protein. There are five isoforms of C1orf43 that are produced as a result of alternative splicing events. The gene encoding C1orf43 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Gene ID: 25912