LSD1 antibody (AA 301-400)

Catalog No. ABIN1714208

The Rabbit Polyclonal anti-LSD1 antibody has been validated for WB and ELISA. It is suitable to detect LSD1 in samples from Human, Mouse and Rat.

Quick Overview for LSD1 antibody (AA 301-400) (ABIN1714208)

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LSD1 Antibody

Binding Specificity: AA 301-400

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KDM1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Alternative Name: KDM1

Background:

Synonyms: Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain protein 2, AOF 2, AOF2, BHC110, BRAF35 HDAC complex protein BHC110, BRAF35-HDAC complex protein BHC110, FAD binding protein BRAF35 HDAC complex, 110 kDa subunit, Flavin containing amine oxidase domain containing protein 2, Flavin-containing amine oxidase domain-containing protein 2, KDM 1, Kdm1a, KDM1A_HUMAN, KIAA0601, LSD 1, LSD1, Lysine K specic demethylase 1, Lysine K specic demethylase 1A, Lysine specic histone demethylase 1, Lysine specic histone demethylase 1A, Lysine-specic histone demethylase 1, Lysine-specic histone demethylase 1A.

Background: Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect