FKBP11 antibody (AA 121-201)

Catalog No. ABIN1714366

Product Details anti-FKBP11 Antibody

Target: FKBP11 (FK506 Binding Protein 11, 19 KDa (FKBP11))

Binding Specificity: AA 121-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FKBP11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FKBP11

Target: FKBP11 (FK506 Binding Protein 11, 19 KDa (FKBP11))

Alternative Name: FKBP11 (FKBP11 Products)

Synonyms: MGC85245 antibody, 1110002O23Rik antibody, FKBP-11 antibody, si:dz202l16.2 antibody, wu:fd54d02 antibody, zgc:110640 antibody, FKBP19 antibody, FK506 binding protein 11 L homeolog antibody, FK506 binding protein 11 antibody, fkbp11.L antibody, FKBP11 antibody, Fkbp11 antibody, fkbp11 antibody

Background:

Synonyms: 19 kDa FK506 binding protein, 19 kDa FK506-binding protein, 19 kDa FKBP, FK506 binding protein 11 19 kDa, FK506 binding protein 11, FK506-binding protein 11, FKB11_HUMAN, FKBP 19, FKBP-11, FKBP-19, Fkbp11, FKBP19, MGC54182, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase, PPIase FKBP11, Rotamase.

Background: The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Immunophilins have also been implicated in protein folding and trafficking within the endoplasmic reticulum (ER). FKBP11 (FK506-binding protein 11), also known as FKBP19 or peptidyl-prolyl cis-trans isomerase FKBP11, is a 201 amino acid single-pass membrane protein belonging to the FKBP-type PPIase family, a group of proteins known to catalyze the folding of proline-containing polypeptides. Containing one PPIase FKBP-type domain, FKBP11 is expressed in secretory tissues such as pancreas, pituitary, stomach, lymph node and salivary gland, and is encoded by a gene that maps to human chromosome 12q13.12. FK506 and rapamycin are known to inhibit FKBP11?s peptidyl-prolyl isomerase activity.

Gene ID: 51303