Thrombopoietin antibody (AA 21-120)

Catalog No. ABIN1714401

This anti-Thrombopoietin antibody is a Rabbit Polyclonal antibody detecting Thrombopoietin in WB, ELISA, ICC, IHC (p), IF (cc), IF (p) and IHC (fro). Suitable for Human, Rat and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for Thrombopoietin antibody (AA 21-120) (ABIN1714401)

Target: Thrombopoietin (THPO)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombopoietin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Thrombopoietin Antibody

Binding Specificity: AA 21-120

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thrombopoietin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Thrombopoietin antibody (ABIN1714401)

Nakamura-Ishizu, Takubo, Kobayashi, Suzuki-Inoue, Suda: "CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow." in: The Journal of experimental medicine, Vol. 212, Issue 12, pp. 2133-46, (2015) (PubMed).

Target Details for Thrombopoietin

Target: Thrombopoietin (THPO)

Alternative Name: Thrombopoietin

Background:

Synonyms: ML, TPO, MGDF, MKCSF, MPLLG, THCYT1, Thrombopoietin, C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Myeloproliferative leukemia virus oncogene ligand, THPO

Background: Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Gene ID: 7066

UniProt: P40225

Pathways: JAK-STAT Signaling, Hormone Activity