GANC antibody (AA 31-130)

Catalog No. ABIN1714452

Cited in 1 publication. The Rabbit Polyclonal anti-GANC antibody (ABIN1714452) specifically detects GANC in WB, ELISA, ICC, IHC (p), IF (cc), IF (p) and IHC (fro). The antibody is reactive with Human and Mouse samples.

Quick Overview for GANC antibody (AA 31-130) (ABIN1714452)

Target: GANC (Glucosidase, Alpha, Neutral C (GANC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GANC Antibody

Binding Specificity: AA 31-130

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GANC antibody (ABIN1714452)

Wang, Liu, Wang, Yang, Li, Ding, Sun, Bai, Li: "Lycium barbarum Polysaccharide Promotes Maturation of Dendritic Cell via Notch Signaling and Strengthens Dendritic Cell Mediated T Lymphocyte Cytotoxicity on Colon Cancer Cell CT26-WT." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 2305683, (2018) (PubMed).

Target Details for GANC

Target: GANC (Glucosidase, Alpha, Neutral C (GANC))

Alternative Name: GANC/Neutral alphaglucosidase C

Background:

Synonyms: Ganc, GANC_HUMAN, Glucosidase alpha neutral C, MGC138256, Neutral alpha glucosidase C, Neutral alpha-glucosidase C, Neutral alphaglucosidase C.

Background: A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, neutral C) is a 914 amino acid protein with -glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked -D-glucose residues and releases -D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Gene ID: 2595